Recommended prerequisite for participation in the module

Content, progress and pedagogy of the module

Learning objectives

Knowledge

• Explain organisation of genomes, proteomes and metabolomes in higher eukaryotes, particularly in human
• Explain how epigenetic, transcriptional, proteomic, posttranslational modifications, metabolic and environmental factors influence disease and patients' response to treatment
• Explain the effects of drugs, biologics and small molecules, on their targets
• Explain how drugs regulate and affect disease progresses and what consequences it has for the disease pathophysiology
• Describe genetic, epigenetic and proteomic biomarkers use in diagnostics, biomarker discovery and validation in a personalised medicine context

Skills

• Apply advanced molecular methods in diagnostics
• Evaluate a choice of diagnostic method or technology
• Choose appropriate databases, algorithms, statistics and parameters in a bioinformatics analysis
• Analyse systems biology data such as DNA sequences, mRNA, proteins as well as integrated Omics type data using bioinformatics
• Use bioinformatical and analytical strategies to solve problems in personalised medicine

Competences

• Combine the theoretical knowledge about genomes and proteomes with the ability to perform laboratory experiments in order to design a diagnostic or analytical protocol
• Evaluate the obtained results based on the theoretical knowledge within pathophysiology and molecular medicine
• Solve and evaluate complex medical issues e.g. design of new diagnostic tools, genetic counselling based on personalised genome sequence data, disease related proteome data, evaluation of scientific articles at the highest international level; integrating knowledge from the previous semesters with the current course

Type of instruction

• Teaching varies between lectures, workshops, (group) exercises and individual study

Exam

Exams

Additional information

Please consult the Moodle page for your semester and contact the semester coordinator if you have academic questions, or the study secretary if you have administrative questions.

All other enquiries may be directed to Helene Nørgaard, secretary of the Study Board.