Prerequisite/Recommended prerequisite for participation in the module

The module builds on knowledge gained in Biomolecuels and Biochemistry I, Biochemistry II or similar

Content, progress and pedagogy of the module

• The structure and organization of the genetic material including DNA, RNA, the bacterial genome and plasmids
• Replication of DNA including segregation and mitosis
• Genetic variation, mutation, repair mechanisms, recombination, mobile genetic elements and transcription factors
• Transcription and translation, operons, RNA synthesis, mRNA splicing, protein synthesis and the genetic code
• Molecular biological methods in theory and practice focusing on methods for genetic modification of microorganisms for production and other biotechnological purposes
• Genomics, transcriptomics and proteomics
• Introduction to simple molecular biology phylogenetical tools

Learning objectives

Knowledge

Students who have passed the module 

• Can account for the central dogma and its implicationscan, account for  the nature, organization and replication of the genetic material in prokaryotes as well as in eukaryotes
• Can account for the structure and regulation of genes including cis-and trans-regulatory elements
• Can account for transcription and translation in prokaryotes as well as in eukaryotes including the operon model, protein synthesis and the genetic code
• Can account for the theory behind central molecular biological methods - especially methods that can be used for modification and monitoring of biotechnologically relevant organisms
• Can understand the principles behind the so-called "omics" technologies
• Can understand the most simple bioinformatics tools

Skills

• Can use selected molecular biological methods
• Can plan a series of experiments to modify an organism from the methods learned during the course
• Can describe the applications of genetically engineered organisms in biotechnology including considerations related to ethics and safety
• Can use blast and elementary algorithms for molecular biological phylogeny

Type of instruction

• Lectures and laboratory exercises

Extent and expected workload

150 hours

Exam

Exams

Name of exam	Molecular Biology
Type of exam	Written exam 4 hours
ECTS	5
Assessment	7-point grading scale
Type of grading	Internal examination
Criteria of assessment	As stated in the Joint Programme Regulations