Molecular Biology

2018/2019

Prerequisite/Recommended prerequisite for participation in the module

The module builds on knowledge gained in Biomolecuels and Biochemistry I, Biochemistry II or similar

Content, progress and pedagogy of the module

  • The structure and organization of the genetic material including DNA, RNA, the bacterial genome and plasmids
  • Replication of DNA including segregation and mitosis
  • Genetic variation, mutation, repair mechanisms, recombination, mobile genetic elements and transcription factors
  • Transcription and translation, operons, RNA synthesis, mRNA splicing, protein synthesis and the genetic code
  • Molecular biological methods in theory and practice focusing on methods for genetic modification of microorganisms for production and other biotechnological purposes
  • Genomics, transcriptomics and proteomics
  • Introduction to simple molecular biology phylogenetical tools

Learning objectives

Knowledge

Students who have passed the module 

  • Can account for the central dogma and its implicationscan, account for  the nature, organization and replication of the genetic material in prokaryotes as well as in eukaryotes
  • Can account for the structure and regulation of genes including cis-and trans-regulatory elements
  • Can account for transcription and translation in prokaryotes as well as in eukaryotes including the operon model, protein synthesis and the genetic code
  • Can account for the theory behind central molecular biological methods - especially methods that can be used for modification and monitoring of biotechnologically relevant organisms
  • Can understand the principles behind the so-called "omics" technologies
  • Can understand the most simple bioinformatics tools

Skills

  • Can use selected molecular biological methods
  • Can plan a series of experiments to modify an organism from the methods learned during the course
  • Can describe the applications of genetically engineered organisms in biotechnology including considerations related to ethics and safety
  • Can use blast and elementary algorithms for molecular biological phylogeny

Type of instruction

  • Lectures and laboratory exercises

Extent and expected workload

150 hours

Exam

Exams

Name of examMolecular Biology
Type of exam
Written exam
4 hours
ECTS5
Assessment7-point grading scale
Type of gradingInternal examination
Criteria of assessmentAs stated in the Joint Programme Regulations

Facts about the module

Danish titleMolekylærbiologi
Module codeK-BBT-B5-5
Module typeCourse
Duration1 semester
SemesterAutumn
ECTS5
Language of instructionEnglish
Empty-place SchemeYes
Location of the lectureCampus Copenhagen
Responsible for the module

Organisation

Study BoardStudy Board of Biotechnology, Chemistry and Environmental Engineering
FacultyFaculty of Engineering and Science