Molecular Biology

2018/2019

Prerequisite/Recommended prerequisite for participation in the module

The module builds on knowledge gained in Biomolecuels and Biochemistry I, Biochemistry II or similar

Content, progress and pedagogy of the module

  • The structure and organization of the genetic material including DNA, RNA, the bacterial genome and plasmids
  • Replication of DNA including segregation and mitosis
  • Genetic variation, mutation, repair mechanisms, recombination, mobile genetic elements and transcription factors
  • Transcription and translation, operons, RNA synthesis, mRNA splicing, protein synthesis and the genetic code
  • Molecular biological methods in theory and practice focusing on methods for genetic modification of microorganisms for production and other biotechnological purposes
  • Genomics, transcriptomics and proteomics
  • Introduction to simple molecular biology phylogenetical tools

Learning objectives

Knowledge

Students who have passed the module 

  • Can account for the central dogma and its implicationscan, account for  the nature, organization and replication of the genetic material in prokaryotes as well as in eukaryotes
  • Can account for the structure and regulation of genes including cis-and trans-regulatory elements
  • Can account for transcription and translation in prokaryotes as well as in eukaryotes including the operon model, protein synthesis and the genetic code
  • Can account for the theory behind central molecular biological methods - especially methods that can be used for modification and monitoring of biotechnologically relevant organisms
  • Can understand the principles behind the so-called "omics" technologies
  • Can understand the most simple bioinformatics tools

Skills

  • Can use selected molecular biological methods
  • Can plan a series of experiments to modify an organism from the methods learned during the course
  • Can describe the applications of genetically engineered organisms in biotechnology including considerations related to ethics and safety
  • Can use blast and elementary algorithms for molecular biological phylogeny

Type of instruction

  • Lectures and laboratory exercises


Extent and expected workload

150 hours

Exam

Exams

Name of examMolecular Biology
Type of exam
Written exam
4 hours
ECTS5
Assessment7-point grading scale
Type of gradingInternal examination
Criteria of assessmentAs stated in the Joint Programme Regulations

Facts about the module

Danish titleMolekylærbiologi
Module codeK-BBT-B5-5
Module typeCourse
Duration1 semester
SemesterAutumn
ECTS5
Language of instructionEnglish
Empty-place SchemeYes
Location of the lectureCampus Copenhagen
Responsible for the module

Organisation

Study BoardStudy Board of Biotechnology, Chemistry and Environmental Engineering
FacultyFaculty of Engineering and Science
SchoolSchool of Engineering and Science